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Marcin Wierzchowski Selected Research

3,4,5,4'-tetramethoxystilbene

5/2020The Effect of 4'-hydroxy-3,4,5-trimetoxystilbene, the Metabolite of Resveratrol Analogue DMU-212, on Growth, Cell Cycle and Apoptosis in DLD-1 and LOVO Colon Cancer Cell Lines.
2/2020The Effect of 3'-Hydroxy-3,4,5,4'-Tetramethoxy -stilbene, the Metabolite of the Resveratrol Analogue DMU-212, on the Motility and Proliferation of Ovarian Cancer Cells.
8/2017Development and validation of HPLC-MS/MS procedure for determination of 3,4,4',5-tetra-methoxystilbene (DMU-212) and its metabolites in ovarian cancer cells and culture medium.
2/2017Role of CYP1A1 in the biological activity of methylated resveratrol analogue, 3,4,5,4'-tetramethoxystilbene (DMU-212) in ovarian cancer A-2780 and non-cancerous HOSE cells.
1/20163'-hydroxy-3,4,5,4'-tetramethoxystilbene, the metabolite of resveratrol analogue DMU-212, inhibits ovarian cancer cell growth in vitro and in a mice xenograft model.
5/2014DMU-212 inhibits tumor growth in xenograft model of human ovarian cancer.
12/2013Different susceptibility of colon cancer DLD-1 and LOVO cell lines to apoptosis induced by DMU-212, a synthetic resveratrol analogue.

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Marcin Wierzchowski Research Topics

Disease

14Neoplasms (Cancer)
06/2021 - 04/2012
6Ovarian Neoplasms (Ovarian Cancer)
02/2020 - 05/2014
3Carcinogenesis
05/2020 - 06/2014
2Colonic Neoplasms (Colon Cancer)
05/2020 - 12/2013
2Breast Neoplasms (Breast Cancer)
07/2018 - 05/2014
1Neoplasm Metastasis (Metastasis)
06/2021
1Tongue Neoplasms (Tongue Neoplasm)
06/2021
1Glioblastoma (Glioblastoma Multiforme)
03/2021
1Myeloid Leukemia (Leukemia, Myelocytic)
11/2020
1Colorectal Neoplasms (Colorectal Cancer)
05/2020
1Melanoma (Melanoma, Malignant)
02/2016
1Carcinoma (Carcinomatosis)
02/2016
1Lymphoma (Lymphomas)
02/2016
1T-Cell Leukemia (Leukemia, T Cell)
02/2014
1Leukemia
02/2014
1Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL)
02/2014
1Gastrointestinal Neoplasms (Gastrointestinal Cancer)
11/2013
1Myoma
04/2012
1Rupture
01/2012
1Rhabdomyosarcoma
07/2010

Drug/Important Bio-Agent (IBA)

14ResveratrolIBA
06/2021 - 08/2012
7StilbenesIBA
03/2021 - 11/2013
73,4,5,4'-tetramethoxystilbeneIBA
05/2020 - 12/2013
2Antineoplastic Agents (Antineoplastics)IBA
05/2020 - 05/2014
2Biological ProductsIBA
02/2020 - 02/2017
2EnzymesIBA
07/2018 - 01/2017
2Estrogens (Estrogen)FDA Link
07/2018 - 01/2017
23,3',4,4'-tetrahydroxystilbeneIBA
01/2015 - 02/2014
2Pharmaceutical PreparationsIBA
01/2015 - 11/2013
23,3',4,4',5,5'-hexahydroxystilbeneIBA
02/2014 - 11/2013
1Phosphotransferases (Kinase)IBA
06/2021
1Gefitinib (Iressa)FDA Link
06/2021
1Tyrosine (L-Tyrosine)FDA Link
06/2021
1CateninsIBA
03/2021
12-methyl-5-nitroimidazoleIBA
01/2020
1PorphyrinsIBA
01/2020
1Proteins (Proteins, Gene)FDA Link
07/2018
1Cytochrome P-450 CYP1A1 (CYP1A1)IBA
02/2017
1Cytostatic AgentsIBA
02/2016
1SuspensionsIBA
02/2016
1SestrinsIBA
01/2016
1CatalaseIBA
01/2015
18-Hydroxy-2'-DeoxyguanosineIBA
01/2015
1Superoxide DismutaseIBA
01/2015
1Reactive Oxygen Species (Oxygen Radicals)IBA
01/2015
1CaspasesIBA
01/2015
1DNA Glycosylases (DNA Glycosylase)IBA
01/2015
1p38 Mitogen-Activated Protein KinasesIBA
01/2015
1Transcription Factor AP-1 (Transcription Factor AP 1)IBA
06/2014
1Transcription Factors (Transcription Factor)IBA
06/2014
1resazurinIBA
02/2014
1PolyphenolsIBA
02/2014
1CA-125 Antigen (CA 125 Antigen)IBA
04/2012
1Chorionic Gonadotropin (Human Chorionic Gonadotropin)FDA LinkGeneric
04/2012
1Acute-Phase Proteins (Acute-Phase Protein)IBA
04/2012
1Anti-Bacterial Agents (Antibiotics)IBA
01/2012

Therapy/Procedure

3Drug Therapy (Chemotherapy)
12/2017 - 07/2010
1Chemoprevention
12/2017
1Photochemotherapy (Photodynamic Therapy)
03/2015
1Therapeutics
05/2014
1Uterine Myomectomy
04/2012
1Bed Rest (Bedrest)
01/2012
1Hysterectomy
07/2010
1Salpingo-oophorectomy
07/2010